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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_2837Hypothetical protein. (42 aa)    
Predicted Functional Partners:
fdxB
Ferredoxin.
 
     0.809
SACE_1053
Hypothetical protein.
  
     0.699
fprC
Ferredoxin reductase; Contains frameshift mutation.
 
     0.654
SACE_5425
Putative DNA-binding protein.
  
     0.637
lexA
Putative repressor of the SOS regulon; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.542
SACE_6869
Hypothetical protein.
  
     0.521
SACE_4628
Hypothetical protein.
  
     0.488
SACE_6937
Protein of unknown function DUF1526.
  
    0.464
SACE_7333
Hypothetical protein.
  
     0.445
SACE_4895
Putative secreted protein.
  
     0.402
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.