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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wrbAFlavodoxin/nitric oxide synthase; Belongs to the WrbA family. (204 aa)    
Predicted Functional Partners:
SACE_2898
Hypothetical protein; Multimeric flavodoxin WrbA.
  
  
 
0.923
wrbA-2
Trp repressor binding protein; Belongs to the WrbA family.
  
  
 
0.905
SACE_3270
Methyltransferase type 12.
     
  0.900
ubiE-3
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
     
  0.900
SACE_2880
Hypothetical protein.
       0.752
pecS
Transcriptional regulator, MarR family.
  
  
 0.707
SACE_0010
Hypothetical protein Rv0007.
   
  
 0.551
SACE_2879
TetR-family transcriptional regulator.
 
     0.529
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
  
 0.517
SACE_2882
Possible transcriptional regulator, ArsR family.
       0.511
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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