Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SACE_3153AMP-dependent synthetase and ligase. (571 aa)    
Predicted Functional Partners:
SACE_3400
acetyl/propionyl-CoA carboxylase alpha subunit.
  
 
 0.821
SACE_6509
acetyl/propionyl-CoA carboxylase alpha subunit.
  
 
 0.821
accC3
Biotin carboxylase.
  
 
 0.785
fadD
acyl-CoA synthase.
  
  
 
0.716
SACE_0603
Hypothetical protein; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
0.709
SACE_1694
Putative long-chain fatty acid ligase.
 
 
0.699
SACE_6950
Putative fatty-acid--CoA ligase.
  
  
 
0.695
SACE_3409
AMP-dependent Acyl-CoA synthetase and ligase.
  
  
 
0.690
SACE_5343
AMP-dependent synthetase and ligase.
 
 
0.683
SACE_5393
long-chain-fatty-acid--CoA ligase.
  
  
 
0.680
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
Server load: low (28%) [HD]