Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SACE_3161Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s). (698 aa)    
Predicted Functional Partners:
SACE_3490
Sensor histidine kinase/response regulator.
  
 
 0.961
SACE_6878
Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
 
0.900
SACE_2183
Hypothetical protein; FOG: GGDEF domain.
 
 
 0.882
SACE_0097
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s).
  
 
 0.832
SACE_2846
Two-component response regulator.
  
 
 0.832
SACE_6414
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s).
  
 
 0.832
SACE_3289
Diguanylate cyclase (GGDEF domain).
 
 
0.692
SACE_4384
Histidine kinase/response regulator hybrid protein.
 
 
0.653
SACE_4369
Histidine kinase-response regulator hybrid protein.
 
 
0.651
SACE_3454
Histidine kinase/response regulator hybrid protein.
 
 
0.644
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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