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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pknDPutative serine/threonine-protein kinase. (473 aa)    
Predicted Functional Partners:
SACE_0048
Protein serine/threonine phosphatases.
 
 0.836
prpB8
Putative magnesium or manganese-dependent protein phosphatase.
 
 
 0.836
SACE_3238
FHA domain containing protein.
 
 
 
 0.767
SACE_3845
FHA domain containing protein.
 
 
 
 0.698
pknB
Serine/threonine protein kinase.
 
 
0.515
phoR
phoR-putative two-component system sensor kinase.
    
 
 0.502
SACE_1780
Possible acetyl-CoA synthetase.
      
 0.477
SACE_0049
FHA domain containing protein.
 
 
 
 0.461
SACE_0050
FHA domain containing protein.
 
 
 
 0.439
SACE_7381
Integral membrane protein MviN.
 
    0.424
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.