Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arsRRegulatory protein, ArsR. (100 aa)    
Predicted Functional Partners:
SACE_3254
Amino acid permease-associated region.
       0.553
trpS-2
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.542
argS
arginyl-tRNA synthetase.
      
 0.524
paaH2
3-hydroxybutyryl-CoA dehydrogenase.
      
 0.521
SACE_5143
Arsenical resistance protein/arsenate reductase.
 
  
 0.492
SACE_5142
Arsenical resistance protein/arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.447
iolE
Sugar phosphate isomerase/epimerase.
       0.431
SACE_3257
Sugar phosphate isomerase/epimerase.
       0.419
SACE_3253
Hypothetical protein.
       0.410
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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