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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
Score
fabG-33-oxoacyl-[acyl-carrier-protein] reductase. (268 aa)    
Predicted Functional Partners:
SACE_5324
Short chain dehydrogenase/reductase SDR.
 
    0.737
SACE_2875
Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004.
  
 
 0.593
SACE_3369
Hypothetical protein.
   
  0.556
eryAII
EryAII Erythromycin polyketide synthase modules 3 and 4; DEBS2.
  
 
 0.553
SACE_2629
Modular ype I polyketide synthase.
  
 
 0.484
SACE_4139
Type I modular polyketide synthase.
  
 
 0.484
SACE_3368
methylated-DNA-(protein)-cysteine S-methyltransferase.
  
    0.473
SACE_3367
RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.464
SACE_3370
Alkylated DNA repair protein.
       0.463
accA
Acetyl carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity). In the N-terminal section; belongs to the AccD/PCCB family.
 
  
 0.401
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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