| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SACE_2800 | vgb | SACE_2800 | SACE_3383 | 3-hydroxyisobutyrate dehydrogenase, NAD-binding protein. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.463 |
| SACE_3791 | vgb | SACE_3791 | SACE_3383 | Glyoxalase/bleomycin resistance protein/dioxygenase. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.426 |
| SACE_5163 | vgb | SACE_5163 | SACE_3383 | Hypothetical protein; SAM-dependent methyltransferases. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.423 |
| choD | vgb | SACE_6705 | SACE_3383 | Cholesterol oxidase. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.470 |
| embC | embC-2 | SACE_0178 | SACE_0179 | Probable arabinosyltransferase, membrane protein. | Integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase). | 0.503 |
| embC | vgb | SACE_0178 | SACE_3383 | Probable arabinosyltransferase, membrane protein. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.417 |
| embC-2 | embC | SACE_0179 | SACE_0178 | Integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase). | Probable arabinosyltransferase, membrane protein. | 0.503 |
| embC-2 | vgb | SACE_0179 | SACE_3383 | Integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase). | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.417 |
| embC-3 | vgb | SACE_0198 | SACE_3383 | Arabinosyl transferase. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.417 |
| embC-4 | vgb | SACE_5074 | SACE_3383 | Putative arabinosyl transferase. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.417 |
| embC-5 | vgb | SACE_5147 | SACE_3383 | Arabinosyl transferase. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.417 |
| ermE | vgb | SACE_0733 | SACE_3383 | N-6-aminoadenine-N-methyltransferase, erythromycinresistance; This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 0.419 |
| vgb | SACE_2800 | SACE_3383 | SACE_2800 | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | 3-hydroxyisobutyrate dehydrogenase, NAD-binding protein. | 0.463 |
| vgb | SACE_3791 | SACE_3383 | SACE_3791 | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | Glyoxalase/bleomycin resistance protein/dioxygenase. | 0.426 |
| vgb | SACE_5163 | SACE_3383 | SACE_5163 | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | Hypothetical protein; SAM-dependent methyltransferases. | 0.423 |
| vgb | choD | SACE_3383 | SACE_6705 | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | Cholesterol oxidase. | 0.470 |
| vgb | embC | SACE_3383 | SACE_0178 | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | Probable arabinosyltransferase, membrane protein. | 0.417 |
| vgb | embC-2 | SACE_3383 | SACE_0179 | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | Integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase). | 0.417 |
| vgb | embC-3 | SACE_3383 | SACE_0198 | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | Arabinosyl transferase. | 0.417 |
| vgb | embC-4 | SACE_3383 | SACE_5074 | Putative hydrolase/lactonase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. | Putative arabinosyl transferase. | 0.417 |