Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SACE_3840Cobalamin (vitamin B12) biosynthesis CbiM protein. (231 aa)    
Predicted Functional Partners:
SACE_3838
Probable ABC cobalt transporter, permease component.
 
 
 0.996
SACE_3837
Cobalt ABC transporter ATP binding protein.
 
 
 0.992
SACE_3839
Hypothetical protein.
 
  
  0.987
cobJ
Putative precorrin methylase.
  
  
 0.798
SACE_5951
precorrin-3B C17-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.707
SACE_1190
Cobalt transport system permease protein.
  
  
 0.642
SACE_5957
uroporphyrin-III C-methyltransferase.
 
   
 0.615
SACE_3836
Acetyltransferase.
       0.448
cobL
precorrin-6Y C(5,15)-methyltransferase (decarboxylating).
  
  
 0.445
SACE_5961
Precorrin-6y C5,15-methyltransferase, subunit CbiE.
  
  
 0.445
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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