Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dhbE-22,3-dihydroxybenzoate-AMP ligase. (541 aa)    
Predicted Functional Partners:
dhbB
Isochorismatase (2,3 dihydro-2,3 dihydroxybenzoate synthase).
 
 
 0.998
dhbA,
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase.
 
 0.995
dhbC
Isochorismate synthase.
 
  
 0.990
SACE_2693
Non-ribosomal peptide synthase.
 
 
0.988
pptA2
Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
  
 
 0.967
SACE_2696
Putative non-ribosomal peptide synthetase.
 
  
0.956
SACE_4287
Putative non-ribosomal peptide synthetase.
 
  
0.925
SACE_4138
Type I PKS modular polyketide synthas.
  
 
 0.899
SACE_2692
MbtH-like protein.
 
  
 0.892
trpE
Anthranilate synthase component I.
 
  
 0.865
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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