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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_4099methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (206 aa)    
Predicted Functional Partners:
SACE_4098
RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.945
SACE_4100
Uncharacterized protein conserved in bacteria.
 
     0.864
phrB
Putative deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.
     
 0.833
SACE_0525
Cold-shock DNA-binding domain protein.
  
  
 0.705
SACE_0594
Cold-shock DNA-binding domain protein.
  
  
 0.705
SACE_1442
Cold-shock DNA-binding domain protein.
  
  
 0.705
SACE_1965
Putative DNA binding protein.
  
  
 0.705
SACE_2658
Cold-shock DNA-binding domain protein.
  
  
 0.705
SACE_3094
Cold-shock DNA-binding domain protein.
  
  
 0.705
SACE_3872
Cold-shock DNA-binding domain protein.
  
  
 0.705
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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