Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SACE_4115Alpha/beta hydrolase fold. (273 aa)    
Predicted Functional Partners:
SACE_1904
Alpha/beta hydrolase.
  
     0.749
SACE_6242
Alpha/beta hydrolase fold.
  
     0.732
SACE_1924
Hydrolase.
  
     0.718
SACE_6290
Similar to hydrolase or acyltransferase (alpha/beta hydrolase superfamily).
  
     0.710
SACE_2557
Hydrolase.
  
     0.694
SACE_3626
Alpha/beta hydrolase fold.
  
     0.681
SACE_0966
3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase.
  
     0.651
SACE_5137
Oxidoreductase.
  
     0.638
SACE_4736
Oxidoreductase.
  
     0.569
SACE_3526
Alpha/beta hydrolase fold.
  
     0.563
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.