STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_4179Hypothetical protein; Predicted acetyltransferase involved in intracellular survival. (404 aa)    
Predicted Functional Partners:
ermE
N-6-aminoadenine-N-methyltransferase, erythromycinresistance; This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
   
  
 0.565
SACE_1435
Competence protein ComEA helix-hairpin-helix region.
  
    0.562
tetV
Drug:proton antiporter.
  
    0.507
SACE_4178
Hypothetical protein.
       0.457
SACE_4180
Hypothetical protein.
       0.445
SACE_0612
Probable multidrug efflux transport protein.
   
    0.436
SACE_0642
Probable multidrug resistance transporter, MFS superfamily.
   
    0.436
SACE_2690
Probable multidrug resistance transporter, MFS superfamily.
   
    0.436
SACE_3205
Transmembrane efflux protein.
   
    0.436
pimH
Integral membrane efflux protein.
   
    0.436
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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