Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hopDPutative squalene/phytoene synthase. (297 aa)    
Predicted Functional Partners:
crtI
Phytoene desaturase.
 
 
 0.986
hopC
Squalene/phytoene dehydrogenase.
  
 0.959
SACE_4328
Dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
 
 0.947
shc1
Squalene--hopene cyclase.
 
  
 0.920
hopE
Squalene/phytoene synthase.
 
   
0.906
SACE_4325
Radical SAM.
 
   
 0.896
ispH
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein (partial match).
 
   
 0.883
SACE_4909
Dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
 
 0.817
uppS-2
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
   
 
 0.815
SACE_3979
Dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.793
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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