Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
exaAProbable quinoprotein ethanol dehydrogenase precursor. (562 aa)    
Predicted Functional Partners:
thcA
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
  
 
 0.917
thcA-2
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
  
 
 0.917
pqqB
Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
 
  
 0.906
aldA
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.905
SACE_2895
Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.905
SACE_3969
Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.905
SACE_4926
Putative betaine aldehyde dehydrogenase oxidoreductase protein; Belongs to the aldehyde dehydrogenase family.
   
 
 0.905
SACE_6565
Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.905
pqqC
Coenzyme PQQ synthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
  
 0.894
pqqE-2
Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
  
 0.811
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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