Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SACE_4489Probable hydroxyacylglutathione hydrolase. (208 aa)    
Predicted Functional Partners:
SACE_4490
NAD/factor-dependent formaldehyde dehydrogenase.
 
    0.903
SACE_3147
NAD/factor-dependent formaldehyde dehydrogenase.
 
    0.607
SACE_4443
NAD/factor-dependent formaldehyde dehydrogenase.
 
    0.594
SACE_4513
NAD/factor-dependent formaldehyde dehydrogenase.
 
    0.586
soxA-2
Sarcosine oxidase (alpha subunit) oxidoreductase protein.
  
 0.569
SACE_7179
Hypothetical protein.
  
     0.502
SACE_4488
Hypothetical protein.
       0.456
glyA2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.421
soxG
Sarcosine oxidase gamma subunit.
       0.400
soxD
Sarcosine oxidase, delta chain.
       0.400
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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