Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
soxGSarcosine oxidase gamma subunit. (199 aa)    
Predicted Functional Partners:
soxA-2
Sarcosine oxidase (alpha subunit) oxidoreductase protein.
 
 0.999
soxD
Sarcosine oxidase, delta chain.
 
 0.999
soxD-2
Sarcosine oxidase, delta chain.
 
 0.997
soxB
Sarcosine oxidase beta subunit.
 
 0.996
soxA-3
Sarcosine oxidase (alpha subunit) oxidoreductase protein.
 
 0.986
soxB-2
Sarcosine oxidase beta subunit.
 
 0.985
SACE_4496
FAD dependent oxidoreductase; Belongs to the GcvT family.
 
 0.982
glyA2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.979
SACE_3149
FAD dependent oxidoreductase; Belongs to the GcvT family.
 
 0.974
SACE_5616
FAD dependent oxidoreductase; Belongs to the GcvT family.
 
 0.972
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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