| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SACE_0773 | SACE_4497 | SACE_0773 | SACE_4497 | 5-formyltetrahydrofolate cyclo-ligase. | Probable methenyltetrahydrofolate cyclohydrolase. | 0.909 |
| SACE_0773 | fhs | SACE_0773 | SACE_5619 | 5-formyltetrahydrofolate cyclo-ligase. | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.403 |
| SACE_0773 | folD | SACE_0773 | SACE_4498 | 5-formyltetrahydrofolate cyclo-ligase. | Putative methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.920 |
| SACE_0773 | folD-2 | SACE_0773 | SACE_6651 | 5-formyltetrahydrofolate cyclo-ligase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.920 |
| SACE_0773 | purN | SACE_0773 | SACE_6665 | 5-formyltetrahydrofolate cyclo-ligase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.926 |
| SACE_4497 | SACE_0773 | SACE_4497 | SACE_0773 | Probable methenyltetrahydrofolate cyclohydrolase. | 5-formyltetrahydrofolate cyclo-ligase. | 0.909 |
| SACE_4497 | fhs | SACE_4497 | SACE_5619 | Probable methenyltetrahydrofolate cyclohydrolase. | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.946 |
| SACE_4497 | folD | SACE_4497 | SACE_4498 | Probable methenyltetrahydrofolate cyclohydrolase. | Putative methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.981 |
| SACE_4497 | folD-2 | SACE_4497 | SACE_6651 | Probable methenyltetrahydrofolate cyclohydrolase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.922 |
| SACE_4497 | folP-3 | SACE_4497 | SACE_4499 | Probable methenyltetrahydrofolate cyclohydrolase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.795 |
| SACE_4497 | gcvT | SACE_4497 | SACE_5701 | Probable methenyltetrahydrofolate cyclohydrolase. | Putative glycine cleavage system protein T (aminomethyltransferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.914 |
| SACE_4497 | purH | SACE_4497 | SACE_6664 | Probable methenyltetrahydrofolate cyclohydrolase. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.908 |
| SACE_4497 | purN | SACE_4497 | SACE_6665 | Probable methenyltetrahydrofolate cyclohydrolase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.900 |
| SACE_4497 | purU | SACE_4497 | SACE_6982 | Probable methenyltetrahydrofolate cyclohydrolase. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.903 |
| SACE_4497 | purU-2 | SACE_4497 | SACE_4502 | Probable methenyltetrahydrofolate cyclohydrolase. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.903 |
| fhs | SACE_0773 | SACE_5619 | SACE_0773 | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 5-formyltetrahydrofolate cyclo-ligase. | 0.403 |
| fhs | SACE_4497 | SACE_5619 | SACE_4497 | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Probable methenyltetrahydrofolate cyclohydrolase. | 0.946 |
| fhs | folD | SACE_5619 | SACE_4498 | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Putative methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.995 |
| fhs | folD-2 | SACE_5619 | SACE_6651 | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.995 |
| fhs | gcvT | SACE_5619 | SACE_5701 | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Putative glycine cleavage system protein T (aminomethyltransferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.928 |