Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdxA34-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (334 aa)    
Predicted Functional Partners:
SACE_4549
4-hydroxythreonine-4-phosphate dehydrogenase.
     0.970
ygbK
Putative membrane protein.
 
     0.782
SACE_4557
Glycosyl hydrolase, BNR repeat.
 
     0.694
SACE_4547
Transcriptional regulator, DeoR family.
 
     0.645
SACE_4550
Extracellular solute-binding protein.
 
     0.627
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
     
 0.581
SACE_4555
Aldo/keto reductase.
 
     0.565
SACE_4554
Oligopeptide ABC transporter (ATP-binding protein).
  
    0.519
SACE_4553
Putative oligopeptide ABC transporter ATP-binding protein.
  
    0.518
SACE_4551
Binding-protein-dependent transport systems membrane component.
       0.505
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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