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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxA34-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (334 aa)    
Predicted Functional Partners:
SACE_4549
4-hydroxythreonine-4-phosphate dehydrogenase.
     0.971
ygbK
Putative membrane protein.
 
     0.789
SACE_4557
Glycosyl hydrolase, BNR repeat.
 
     0.695
SACE_4547
Transcriptional regulator, DeoR family.
 
     0.646
SACE_4550
Extracellular solute-binding protein.
 
     0.627
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
     
 0.574
SACE_4555
Aldo/keto reductase.
 
     0.566
SACE_4554
Oligopeptide ABC transporter (ATP-binding protein).
       0.518
SACE_4553
Putative oligopeptide ABC transporter ATP-binding protein.
  
    0.514
SACE_4551
Binding-protein-dependent transport systems membrane component.
       0.505
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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