Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SACE_4559Mn2+ and Fe2+ transporters of the NRAMP family-like protein. (471 aa)    
Predicted Functional Partners:
SACE_4556
HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
 
     0.619
SACE_4557
Glycosyl hydrolase, BNR repeat.
       0.539
serA-3
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.537
SACE_4560
O-methyltransferase, family 2.
 
     0.481
SACE_2547
Mn(2+) transport protein, NramP family.
  
     0.476
SACE_2578
Hypothetical protein.
  
    0.461
SACE_2998
Type I phosphodiesterase/nucleotide pyrophosphatase.
 
 
 0.454
hemH
Ferrochelatase precursor; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.408
SACE_6030
Iron (metal) dependent repressor, DtxR family.
 
  
 0.404
SACE_4555
Aldo/keto reductase.
    
  0.400
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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