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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_4584Possible sulfopyruvate decarboxylase beta subunit. (194 aa)    
Predicted Functional Partners:
SACE_4585
Probable sulfopyruvate decarboxylase alpha subunit.
 
   
 0.963
ilvN
Acetolactate synthase small subunit.
  
 
 0.843
SACE_4582
Hypothetical protein.
 
     0.604
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.563
SACE_4583
Alpha-ketoglutarate transporter, MFS superfamily.
     
 0.516
citE3-2
Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
       0.514
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 0.513
leuB1
3-isopropylmalate dehydrogenase.
 
 
 0.496
SACE_3639
Serine--glyoxylate aminotransferase.
 
 
 0.476
SACE_4586
Probable hydrolase.
       0.470
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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