close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_4652Protein kinase/transcriptional regulator, LuxR family. (767 aa)    
Predicted Functional Partners:
SACE_6878
Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
 
 0.540
SACE_0145
Two-component system sensor kinase.
 
 
 0.521
SACE_4654
Protein kinase/transcriptional regulator, LuxR family.
 
   
0.518
SACE_3490
Sensor histidine kinase/response regulator.
 
 
 0.516
SACE_4653
Protein kinase/transcriptional regulator, LuxR family.
 
  
0.485
SACE_6703
Two-component system sensor kinase.
 
   0.462
SACE_3026
Putative transcriptional activator of the SARP family.
 
 
 0.423
cdaR-2
Transcriptional regulator.
 
  
 0.415
SACE_0097
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s).
  
  
 0.413
SACE_2846
Two-component response regulator.
  
  
 0.413
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.