Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mmsA1Methylmalonate-semialdehyde dehydrogenase (acylating). (505 aa)    
Predicted Functional Partners:
fadA6
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.935
bkdC2
Putative dihydrolipoamide acyltransferase component E2.
  
 
 0.934
mmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
 
 
 0.930
SACE_3418
Aminotransferase class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.926
SACE_1824
Acetyl-coa acetyltransferase (thiolase); Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.923
gabT2
4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.923
fadA
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.923
gabT
4-aminobutyrate aminotransferase, PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.923
SACE_1371
6-phosphogluconate dehydrogenase, NAD-binding.
 
 
 0.921
SACE_3558
6-phosphogluconate dehydrogenase, NAD-binding.
 
 
 0.921
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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