Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SACE_4885Hypothetical protein; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase. (297 aa)    
Predicted Functional Partners:
SACE_1947
Luciferase-like.
  
     0.733
SACE_1340
DsbA oxidoreductase.
   
    0.695
SACE_4417
N5,N10-methylenetetrahydromethanopterin reductase-related protein.
  
     0.664
SACE_1248
Mycobacterium tuberculosis paralogous family 11.
  
   
 0.625
SACE_0781
NADPH-dependent FMN reductase.
  
 
 0.620
SACE_0111
Pyridoxamine 5'-phosphate oxidase-related,FMN-binding.
 
     0.576
SACE_1633
Probable alkanesulfonate monooxygenase.
  
     0.560
SACE_3706
Pyridoxamine 5'-phosphate oxidase-related,FMN-binding protein.
  
     0.534
SACE_0359
Pyridoxamine 5'-phosphate oxidase-related,FMN-binding protein.
  
     0.528
SACE_5752
Hypothetical protein.
  
     0.528
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
Server load: low (12%) [HD]