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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_4940Fructuronate reductase; Belongs to the mannitol dehydrogenase family. (491 aa)    
Predicted Functional Partners:
hrmI
Hexuronic acid isomerase.
 
 
 0.983
SACE_4937
Mandelate racemase/starvation sensing protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.966
SACE_5057
Mandelate racemase/starvation sensing protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.949
mtlD
Mannitol dehydrogenase.
  
  
 
0.924
idnD-2
Putative zinc-binding alcohol dehydrogenase.
 
   
 0.739
ydfJ
Putative membrane transport protein.
 
   
 0.631
SACE_5173
D-galactarate dehydratase/altronate hydrolase-like.
 
  
 0.620
SACE_4936
Probable 2-dehydro-3-deoxy-phosphogluconate aldolase.
 
  
 0.560
kdgK
2-keto-3-deoxygluconate kinase.
 
   
 0.549
SACE_4162
ABC sugar transporter, substrate-binding component.
 
    0.547
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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