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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACE_4949Short-chain dehydrogenase/reductase SDR. (249 aa)    
Predicted Functional Partners:
SACE_2341
Oxidoreductase short-chain dehydrogenase/reductase family.
 
   0.723
SACE_2257
Oxidoreductase, short-chain dehydrogenase/reductase family.
 
    0.654
SACE_5391
Oxidoreductase short-chain dehydrogenase/reductase family.
 
   0.566
SACE_4950
Short-chain dehydrogenase/reductase SDR.
 
    
0.559
SACE_4948
TetR-family transcriptional regulator.
       0.538
SACE_5568
Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    0.522
SACE_2620
Modular polyketide synthase; Similar to StiA and MxaF proteins from Stigmatella aurantiaca.
  
 
 0.484
SACE_4947
Hypothetical protein.
       0.450
SACE_2875
Modular polyketide synthase-; Modular PKS with 1 AHBA loading domain similar to GdmAI, and two extension modules, first module has complete set of the reductive domains, and the other one didn't have any reductive domains. Found by M.Oliynyk and sequenced by M.Samborskyy (M0ERY) in 2004/02. If it is active, than it can be responsible for the production of the aromatic poliketide antibiotic with low molecular weight. Thanks to the B. Ostash, A. Luzhetsky and Y. Rebets for help with annotation of this cluster in 2004.
  
 
 0.443
SACE_0023
Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.436
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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