Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SACE_5231Two-component system response regulator. (230 aa)    
Predicted Functional Partners:
SACE_5230
Two-component system sensor kinase.
 
 
 0.957
SACE_0145
Two-component system sensor kinase.
 
 
 0.833
SACE_1918
Two-component system sensor kinase.
 
 
 0.815
SACE_7263
Two-component system sensor kinase.
 
 
 0.815
SACE_1659
Two-component system sensor kinase.
 
 
 0.814
SACE_1705
Two component system sensor kinase.
 
 
 0.814
SACE_3088
Two-component system sensor kinase.
 
 
 0.814
SACE_7250
Hypothetical protein; Signal transduction histidine kinase.
 
 
 0.804
SACE_6703
Two-component system sensor kinase.
 
 
 0.797
SACE_6627
Two-component system sensor kinase.
 
 
 0.793
Your Current Organism:
Saccharopolyspora erythraea
NCBI taxonomy Id: 405948
Other names: S. erythraea NRRL 2338, Saccharopolyspora erythraea ATCC 11635, Saccharopolyspora erythraea DSM 40517, Saccharopolyspora erythraea JCM 4748, Saccharopolyspora erythraea NRRL 2338, Saccharopolyspora erythraea str. NRRL 2338, Saccharopolyspora erythraea strain NRRL 2338
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