node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEO49948.1 | SEO65890.1 | SAMN04488052_101390 | SAMN04488052_10231 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Amidohydrolase family protein. | 0.683 |
SEO49948.1 | SEO82370.1 | SAMN04488052_101390 | SAMN04488052_103213 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.811 |
SEO49948.1 | SEP18807.1 | SAMN04488052_101390 | SAMN04488052_11536 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Imidazolonepropionase. | 0.426 |
SEO49948.1 | mtaD | SAMN04488052_101390 | SAMN04488052_102258 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Cytosine/adenosine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.858 |
SEO49948.1 | mtnP | SAMN04488052_101390 | SAMN04488052_1094 | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.664 |
SEO65890.1 | SEO49948.1 | SAMN04488052_10231 | SAMN04488052_101390 | Amidohydrolase family protein. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.683 |
SEO65890.1 | SEP18807.1 | SAMN04488052_10231 | SAMN04488052_11536 | Amidohydrolase family protein. | Imidazolonepropionase. | 0.492 |
SEO65890.1 | mtnP | SAMN04488052_10231 | SAMN04488052_1094 | Amidohydrolase family protein. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.495 |
SEO79909.1 | SEP18807.1 | SAMN04488052_10377 | SAMN04488052_11536 | Tyrosine ammonia-lyase. | Imidazolonepropionase. | 0.954 |
SEO82261.1 | SEP18807.1 | SAMN04488052_103207 | SAMN04488052_11536 | Transcriptional regulator, IclR family. | Imidazolonepropionase. | 0.401 |
SEO82370.1 | SEO49948.1 | SAMN04488052_103213 | SAMN04488052_101390 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.811 |
SEO82370.1 | SEP18807.1 | SAMN04488052_103213 | SAMN04488052_11536 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Imidazolonepropionase. | 0.492 |
SEO82370.1 | mtnP | SAMN04488052_103213 | SAMN04488052_1094 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.495 |
SEP18781.1 | SEP18807.1 | SAMN04488052_11535 | SAMN04488052_11536 | Regulatory protein, luxR family. | Imidazolonepropionase. | 0.584 |
SEP18781.1 | SEP18820.1 | SAMN04488052_11535 | SAMN04488052_11537 | Regulatory protein, luxR family. | Hypothetical protein. | 0.421 |
SEP18807.1 | SEO49948.1 | SAMN04488052_11536 | SAMN04488052_101390 | Imidazolonepropionase. | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.426 |
SEP18807.1 | SEO65890.1 | SAMN04488052_11536 | SAMN04488052_10231 | Imidazolonepropionase. | Amidohydrolase family protein. | 0.492 |
SEP18807.1 | SEO79909.1 | SAMN04488052_11536 | SAMN04488052_10377 | Imidazolonepropionase. | Tyrosine ammonia-lyase. | 0.954 |
SEP18807.1 | SEO82261.1 | SAMN04488052_11536 | SAMN04488052_103207 | Imidazolonepropionase. | Transcriptional regulator, IclR family. | 0.401 |
SEP18807.1 | SEO82370.1 | SAMN04488052_11536 | SAMN04488052_103213 | Imidazolonepropionase. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.492 |