STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mfnAPyridoxal-dependent decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (384 aa)    
Predicted Functional Partners:
ABR55334.1
PFAM: protein of unknown function DUF201; KEGG: mmp:MMP0564 hypothetical protein.
    
 0.977
ABR54522.1
PFAM: Protein of unknown function DUF137; KEGG: mmp:MMP1306 hypothetical protein.
 
  
 0.931
ABR54303.1
PFAM: aminotransferase class I and II; KEGG: mmp:MMP1072 aminotransferase (subgroup I) similar to aromatic aminotransferase.
  
 
 0.926
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mmp:MMP1216 histidinol-phosphate aminotransferase.
    
 0.915
ABR54121.1
TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase class-II; asparagine synthase; KEGG: mmp:MMP0918 asparagine synthetase (glutamine-hydrolyzing).
 
  
 0.862
argG
PFAM: argininosuccinate synthase; ExsB family protein; KEGG: mmp:MMP0073 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
    
 0.834
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.822
pyrB
TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: mmp:MMP1659 aspartate carbamoyltransferase; catalytic subunit.
    
  0.805
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
    
  0.803
ABR54985.1
PFAM: Hydantoinase/oxoprolinase; KEGG: mmp:MMP0072 hypothetical protein.
     
 0.774
Your Current Organism:
Methanococcus vannielii
NCBI taxonomy Id: 406327
Other names: M. vannielii SB, Methanococcus vannielii SB, Methanococcus vannielii str. SB, Methanococcus vannielii strain SB
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