STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mmp:MMP0224 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (427 aa)    
Predicted Functional Partners:
ABR54478.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mmp:MMP1258 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.997
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.997
ABR53963.1
TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; KEGG: mmp:MMP0872 porphobilinogen deaminase.
 
  
 0.959
ABR55278.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.860
ABR55133.1
KEGG: mmp:MMP0223 hypothetical protein.
  
    0.839
ABR54198.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mmp:MMP0966 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
     
 0.798
ABR55001.1
TIGRFAM: siroheme synthase; KEGG: mmp:MMP0089 precorrin-2 oxidase / ferrochelatase.
     
 0.664
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
     
 0.650
ABR55238.1
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: mmp:MMP0330 precorrin-8X methylmutase CbiC/CobH.
     
 0.643
ABR55132.1
KEGG: mmp:MMP0222 hypothetical protein.
       0.642
Your Current Organism:
Methanococcus vannielii
NCBI taxonomy Id: 406327
Other names: M. vannielii SB, Methanococcus vannielii SB, Methanococcus vannielii str. SB, Methanococcus vannielii strain SB
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