STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tgtAArchaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (649 aa)    
Predicted Functional Partners:
ABR54812.1
PFAM: PUA domain containing protein; KEGG: mmp:MMP1595 archaeosine tRNA-ribosyltransferase.
 
 
 0.924
truB
Putative rRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
  
 0.895
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
   
 0.856
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
   
 0.850
ABR54591.1
PFAM: tRNA methyltransferase complex GCD14 subunit; KEGG: mmp:MMP1375 SAM (and some other nucleotide) binding motif.
  
  
 0.834
ABR55163.1
PFAM: CoA-binding domain protein; KEGG: mmp:MMP0253 acetyl-CoA synthetase (ADP-forming), alpha and beta subunits.
   
   0.786
ABR55052.1
PFAM: putative RNA methylase; THUMP domain protein; KEGG: mmp:MMP0149 putative methyltransferase.
 
  
 0.744
pth
Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
       0.740
ABR54072.1
Hypothetical protein.
     
 0.691
ABR54471.1
KEGG: mmp:MMP1250 6-pyruvoyl tetrahydropterin synthase.
     
 0.691
Your Current Organism:
Methanococcus vannielii
NCBI taxonomy Id: 406327
Other names: M. vannielii SB, Methanococcus vannielii SB, Methanococcus vannielii str. SB, Methanococcus vannielii strain SB
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.