STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfiBPutative outer membrane protein. (161 aa)    
Predicted Functional Partners:
XNC1_2837
Conserved hypothetical protein.
 
 
 
 0.930
XNC1_2836
Conserved hypothetical protein.
 
  
 0.877
tolB
Required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
 
 0.749
XNC1_2522
Conserved hypothetical protein with OmpA/MotB domains (probable component of SST VI cluster); Homologs of previously reported genes of unknown function.
 
 
 0.599
skp
Periplasmic molecular chaperone for outer membrane proteins; Belongs to the skp family.
  
 
 0.591
XNC1_4507
Conserved hypothetical protein.
  
 
 0.572
mltD
Lytic murein transglycosylase C, membrane-bound.
 
 
 
 0.571
rtxA
Toxin RtxA; Function of homologous gene experimentally demonstrated in an other organism; factor.
  
  
 0.521
rpsL
30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 
 0.490
rpsF
30S ribosomal subunit protein S6; Binds together with S18 to 16S ribosomal RNA.
   
   0.488
Your Current Organism:
Xenorhabdus nematophila
NCBI taxonomy Id: 406817
Other names: X. nematophila ATCC 19061, Xenorhabdus nematophila ATCC 19061, Xenorhabdus nematophila str. ATCC 19061, Xenorhabdus nematophila strain ATCC 19061
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.