node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceB | ackA | XBJ1_4009 | XBJ1_2934 | Malate synthase A. | Acetate kinase A (propionate kinase 2); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.783 |
aceB | acs | XBJ1_4009 | XBJ1_0050 | Malate synthase A. | acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] | 0.955 |
aceB | adhE | XBJ1_4009 | XBJ1_2430 | Malate synthase A. | Multifunctional: acetaldehyde-CoA dehydrogenase (N-terminal); iron-dependent alcohol dehydrogenase (C-terminal); pyruvate-formate lyase deactivase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.916 |
aceB | fadB | XBJ1_4009 | XBJ1_0517 | Malate synthase A. | Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.702 |
aceB | fadJ | XBJ1_4009 | XBJ1_2992 | Malate synthase A. | Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.702 |
aceB | gltA | XBJ1_4009 | XBJ1_1062 | Malate synthase A. | Citrate synthase; Belongs to the citrate synthase family. | 0.955 |
aceB | leuA | XBJ1_4009 | XBJ1_3493 | Malate synthase A. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.914 |
aceB | prpC | XBJ1_4009 | XBJ1_1345 | Malate synthase A. | Methylcitrate synthase (citrate synthase 2); Belongs to the citrate synthase family. | 0.571 |
aceB | pta | XBJ1_4009 | XBJ1_2935 | Malate synthase A. | Phosphotransacetylase (phosphate acetyltransferase); Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.969 |
ackA | aceB | XBJ1_2934 | XBJ1_4009 | Acetate kinase A (propionate kinase 2); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Malate synthase A. | 0.783 |
ackA | acs | XBJ1_2934 | XBJ1_0050 | Acetate kinase A (propionate kinase 2); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] | 0.925 |
ackA | adhE | XBJ1_2934 | XBJ1_2430 | Acetate kinase A (propionate kinase 2); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Multifunctional: acetaldehyde-CoA dehydrogenase (N-terminal); iron-dependent alcohol dehydrogenase (C-terminal); pyruvate-formate lyase deactivase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.554 |
ackA | aldB | XBJ1_2934 | XBJ1_3649 | Acetate kinase A (propionate kinase 2); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Aldehyde dehydrogenase B (lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. | 0.915 |
ackA | pta | XBJ1_2934 | XBJ1_2935 | Acetate kinase A (propionate kinase 2); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Phosphotransacetylase (phosphate acetyltransferase); Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.999 |
acs | aceB | XBJ1_0050 | XBJ1_4009 | acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] | Malate synthase A. | 0.955 |
acs | ackA | XBJ1_0050 | XBJ1_2934 | acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] | Acetate kinase A (propionate kinase 2); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.925 |
acs | adhE | XBJ1_0050 | XBJ1_2430 | acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] | Multifunctional: acetaldehyde-CoA dehydrogenase (N-terminal); iron-dependent alcohol dehydrogenase (C-terminal); pyruvate-formate lyase deactivase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.945 |
acs | aldB | XBJ1_0050 | XBJ1_3649 | acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] | Aldehyde dehydrogenase B (lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. | 0.929 |
acs | fadB | XBJ1_0050 | XBJ1_0517 | acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] | Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.930 |
acs | fadJ | XBJ1_0050 | XBJ1_2992 | acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compo [...] | Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.924 |