STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmhBD,D-heptose 1,7-bisphosphate phosphatase. (188 aa)    
Predicted Functional Partners:
lpcA
D-sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.988
rfaE
Putative bifunctional ADP-L-glycero-D-manno-heptose synthase: putaive kinase (N-terminal); Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
  
 0.985
yraO
Putative phosphoheptose isomerase with phosphosugar-binding domain; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.
  
 0.964
rfaF
ADP-heptose; LPS heptosyltransferase II.
   
 0.929
hisI
Bifunctional: phosphoribosyl-AMP cyclohydrolase (N-terminal); phosphoribosyl-ATP pyrophosphatase (C-terminal); In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.927
rfaQ
Lipopolysaccharide core biosynthesis; modification of heptose region of core.
 
   
 0.700
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.656
hisH
Glutamine amidotransferase, subunit with HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.618
hisD
Bifunctional HisD: L-histidinal:NAD+ dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
  
 0.605
hisF
Imidazole glycerol phosphate synthase, subunit with HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.605
Your Current Organism:
Xenorhabdus bovienii
NCBI taxonomy Id: 406818
Other names: X. bovienii SS-2004, Xenorhabdus bovienii SS-2004, Xenorhabdus bovienii str. SS-2004, Xenorhabdus bovienii strain SS-2004
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