STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadRTranscriptional regulator of NAD biosynthesis; regulator of PnuC activity; NMN adenylyltransferase. (408 aa)    
Predicted Functional Partners:
cobB
Putative enzyme with DHS-like NAD/FAD-binding domain; Belongs to the sirtuin family. Class III subfamily.
   
 
 0.996
nadE
Putative glutamine-dependent NAD(+) synthetase (NAD(+) synthase [glutamine-hydrolyzing]) (NadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.951
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.950
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
    
 0.948
XBJ1_3288
17.2 kDa protein 1 in recA 5'region; Belongs to the CinA family.
    
 0.947
XBJ1_3339
Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family.
   
    0.940
XBJ1_0136
Conserved hypothetical protein.
   
    0.936
nadD
Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-requiring; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.934
ushA
Bifunctional: UDP-sugar hydrolase; 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
     
 0.910
deoD
Purine-nucleoside phosphorylase.
    
 0.909
Your Current Organism:
Xenorhabdus bovienii
NCBI taxonomy Id: 406818
Other names: X. bovienii SS-2004, Xenorhabdus bovienii SS-2004, Xenorhabdus bovienii str. SS-2004, Xenorhabdus bovienii strain SS-2004
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