STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMK16613.1Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins. (147 aa)    
Predicted Functional Partners:
AMK17665.1
COG0492 Thioredoxin reductase.
 
 
 0.790
AMK16614.1
COG0450 Peroxiredoxin.
  
 
 0.669
AMK16612.1
COG0450 Peroxiredoxin.
       0.590
AMK16615.1
COG0640 Predicted transcriptional regulators.
     
 0.562
AMK19723.1
COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.556
AMK17424.1
Thiol:disulfide interchange protein; COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis.
   
 
 0.539
AMK19460.1
COG0067 Glutamate synthase domain 1.
   
 
 0.511
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
 
  
 0.496
AMK18575.1
COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.465
hslU
ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.
  
 
 0.463
Your Current Organism:
Sphingobium sp. MI1205
NCBI taxonomy Id: 407020
Other names: S. sp. MI1205
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.