node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMK17454.1 | AMK17933.1 | K663_05345 | K663_07760 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.825 |
AMK17454.1 | AMK18517.1 | K663_05345 | K663_10690 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.567 |
AMK17454.1 | AMK19794.1 | K663_05345 | K663_17166 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.919 |
AMK17454.1 | sdhA | K663_05345 | K663_13265 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.474 |
AMK17454.1 | sdhB | K663_05345 | K663_05315 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.646 |
AMK17454.1 | sucA | K663_05345 | K663_05340 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.999 |
AMK17454.1 | sucC | K663_05345 | K663_11500 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.965 |
AMK17454.1 | sucD | K663_05345 | K663_05335 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.982 |
AMK17933.1 | AMK17454.1 | K663_07760 | K663_05345 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.825 |
AMK17933.1 | AMK18517.1 | K663_07760 | K663_10690 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.886 |
AMK17933.1 | AMK19794.1 | K663_07760 | K663_17166 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.825 |
AMK17933.1 | sdhA | K663_07760 | K663_13265 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.437 |
AMK17933.1 | sdhB | K663_07760 | K663_05315 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.542 |
AMK17933.1 | sucA | K663_07760 | K663_05340 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. | 0.475 |
AMK17933.1 | sucC | K663_07760 | K663_11500 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.968 |
AMK17933.1 | sucD | K663_07760 | K663_05335 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.968 |
AMK18517.1 | AMK17454.1 | K663_10690 | K663_05345 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.567 |
AMK18517.1 | AMK17933.1 | K663_10690 | K663_07760 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.886 |
AMK18517.1 | AMK19032.1 | K663_10690 | K663_13270 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | COG2142 Succinate dehydrogenase, hydrophobic anchor subunit. | 0.605 |
AMK18517.1 | AMK19033.1 | K663_10690 | K663_13275 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.774 |