STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEK57077.1DNA polymerase-3 subunit alpha. (983 aa)    
Predicted Functional Partners:
SEM04164.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
    
 0.997
SEM27230.1
DNA polymerase III, delta subunit.
  
 0.997
SEL84836.1
DNA polymerase-3 subunit delta'.
  
 0.995
dnaX
DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.995
SEK57124.1
DNA polymerase-3 subunit epsilon.
 
 
 0.971
SEL40495.1
DNA polymerase III, alpha subunit.
  
 
0.961
SEL37994.1
DNA polymerase-3 subunit epsilon.
    
 0.954
dinB
DNA polymerase-4; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 0.950
SEK60026.1
Single-strand DNA-binding protein.
    
 0.944
SEL73868.1
Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
 0.944
Your Current Organism:
Pseudosphingobacterium domesticum
NCBI taxonomy Id: 407022
Other names: CCUG 54353, DSM 18733, LMG 23837, LMG:23837, Olivibacter domesticus, P. domesticum, Pseudosphingobacterium domesticum Vaz-Moreira et al. 2007 emend. Hahnke et al. 2016, strain DC-186
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.