node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEK50031.1 | SEK92659.1 | SAMN05661044_00390 | SAMN05661044_01525 | Molecular chaperone HtpG. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.665 |
SEK50031.1 | SEL85281.1 | SAMN05661044_00390 | SAMN05661044_03571 | Molecular chaperone HtpG. | Curved DNA-binding protein. | 0.999 |
SEK50031.1 | SEM60238.1 | SAMN05661044_00390 | SAMN05661044_05602 | Molecular chaperone HtpG. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.665 |
SEK50031.1 | clpB | SAMN05661044_00390 | SAMN05661044_02230 | Molecular chaperone HtpG. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.868 |
SEK50031.1 | clpP | SAMN05661044_00390 | SAMN05661044_02480 | Molecular chaperone HtpG. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.488 |
SEK50031.1 | clpP-2 | SAMN05661044_00390 | SAMN05661044_02622 | Molecular chaperone HtpG. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.488 |
SEK50031.1 | dnaJ | SAMN05661044_00390 | SAMN05661044_02265 | Molecular chaperone HtpG. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.999 |
SEK50031.1 | dnaK | SAMN05661044_00390 | SAMN05661044_04064 | Molecular chaperone HtpG. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
SEK50031.1 | grpE | SAMN05661044_00390 | SAMN05661044_02264 | Molecular chaperone HtpG. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.882 |
SEK92659.1 | SEK50031.1 | SAMN05661044_01525 | SAMN05661044_00390 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone HtpG. | 0.665 |
SEK92659.1 | SEL85281.1 | SAMN05661044_01525 | SAMN05661044_03571 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Curved DNA-binding protein. | 0.598 |
SEK92659.1 | clpB | SAMN05661044_01525 | SAMN05661044_02230 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.911 |
SEK92659.1 | dnaJ | SAMN05661044_01525 | SAMN05661044_02265 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.596 |
SEK92659.1 | dnaK | SAMN05661044_01525 | SAMN05661044_04064 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.659 |
SEK92659.1 | grpE | SAMN05661044_01525 | SAMN05661044_02264 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.601 |
SEL85281.1 | SEK50031.1 | SAMN05661044_03571 | SAMN05661044_00390 | Curved DNA-binding protein. | Molecular chaperone HtpG. | 0.999 |
SEL85281.1 | SEK92659.1 | SAMN05661044_03571 | SAMN05661044_01525 | Curved DNA-binding protein. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.598 |
SEL85281.1 | SEM60238.1 | SAMN05661044_03571 | SAMN05661044_05602 | Curved DNA-binding protein. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.598 |
SEL85281.1 | clpB | SAMN05661044_03571 | SAMN05661044_02230 | Curved DNA-binding protein. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.899 |
SEL85281.1 | clpP | SAMN05661044_03571 | SAMN05661044_02480 | Curved DNA-binding protein. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.581 |