STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKG73759.1DNA-binding protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. (111 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.964
ftsY
Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
  
  
 0.886
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.873
smc
Hypothetical protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
    0.863
AKG73792.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.757
AKG73930.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0297 family.
  
     0.752
whiA
Sporulation regulator WhiA; Involved in cell division and chromosome segregation.
  
  
 0.740
AKG73987.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.735
AKG73747.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.718
fapR
Fatty acid biosynthesis transcriptional regulator; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
 
     0.693
Your Current Organism:
Salinicoccus halodurans
NCBI taxonomy Id: 407035
Other names: CGMCC 1.6501, DSM 19336, S. halodurans, Salinicoccus halodurans Wang et al. 2008, Salinicoccus sp. W24, strain W24
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