STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroKHypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (161 aa)    
Predicted Functional Partners:
aroA
Hypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.986
AKG74080.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.980
aroE
Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 
 0.977
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.838
AKG75292.1
Competence protein ComGC; Required for transformation and DNA binding.
       0.648
AKG73183.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.626
AKG74014.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.622
AKG74015.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.622
AKG72920.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.615
AKG72918.1
Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.574
Your Current Organism:
Salinicoccus halodurans
NCBI taxonomy Id: 407035
Other names: CGMCC 1.6501, DSM 19336, S. halodurans, Salinicoccus halodurans Wang et al. 2008, Salinicoccus sp. W24, strain W24
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