| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0194 | THII_0201 | THII_0194 | THII_0201 | Xanthine dehydrogenase. | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.554 |
| THII_0194 | THII_0202 | THII_0194 | THII_0202 | Xanthine dehydrogenase. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.900 |
| THII_0201 | THII_0194 | THII_0201 | THII_0194 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Xanthine dehydrogenase. | 0.554 |
| THII_0201 | THII_0202 | THII_0201 | THII_0202 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.923 |
| THII_0201 | THII_0203 | THII_0201 | THII_0203 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Hypothetical protein. | 0.519 |
| THII_0201 | THII_2650 | THII_0201 | THII_2650 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; Belongs to the 5'-nucleotidase family. | 0.552 |
| THII_0201 | THII_2722 | THII_0201 | THII_2722 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.717 |
| THII_0201 | THII_3051 | THII_0201 | THII_3051 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Putative spermidine synthase with an N-terminal membrane domain. | 0.408 |
| THII_0201 | guaA | THII_0201 | THII_3737 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.607 |
| THII_0201 | mtaD | THII_0201 | THII_3021 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.974 |
| THII_0201 | mtnA | THII_0201 | THII_1317 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | S-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.971 |
| THII_0201 | prmC | THII_0201 | THII_0200 | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | hemK protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.779 |
| THII_0202 | THII_0194 | THII_0202 | THII_0194 | Hypoxanthine-guanine phosphoribosyltransferase. | Xanthine dehydrogenase. | 0.900 |
| THII_0202 | THII_0201 | THII_0202 | THII_0201 | Hypoxanthine-guanine phosphoribosyltransferase. | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.923 |
| THII_0202 | THII_0203 | THII_0202 | THII_0203 | Hypoxanthine-guanine phosphoribosyltransferase. | Hypothetical protein. | 0.519 |
| THII_0202 | guaA | THII_0202 | THII_3737 | Hypoxanthine-guanine phosphoribosyltransferase. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.950 |
| THII_0202 | prmC | THII_0202 | THII_0200 | Hypoxanthine-guanine phosphoribosyltransferase. | hemK protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.779 |
| THII_0203 | THII_0201 | THII_0203 | THII_0201 | Hypothetical protein. | 5''-deoxy-5''-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.519 |
| THII_0203 | THII_0202 | THII_0203 | THII_0202 | Hypothetical protein. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.519 |
| THII_0203 | prmC | THII_0203 | THII_0200 | Hypothetical protein. | hemK protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.519 |