Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
THII_0463Bifunctional malic enzyme oxidoreductase/phosphotransacetylase. (781 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.989
THII_0534
Malate synthase A; Belongs to the malate synthase family.
  
 
 0.979
THII_3339
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.969
THII_3214
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
 0.966
THII_3499
Pyruvate dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.960
THII_3692
Pyruvate:ferredoxin oxidoreductase, beta subunit.
   
 0.953
THII_3694
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
    
 0.952
THII_3783
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.952
THII_3693
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
    
 0.951
THII_2332
Acetolactate synthase, large subunit, biosynthetic type.
  
 0.944
Your Current Organism:
Thioploca ingrica
NCBI taxonomy Id: 40754
Other names: T. ingrica
Server load: low (14%) [HD]