| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_1024 | THII_1025 | THII_1024 | THII_1025 | Transcriptional regulator, SpoVT_AbrB family. | Metallo-beta-lactamase family protein. | 0.477 |
| THII_1024 | THII_1026 | THII_1024 | THII_1026 | Transcriptional regulator, SpoVT_AbrB family. | Folate-binding protein YgfZ; Belongs to the GcvT family. | 0.468 |
| THII_1025 | THII_1024 | THII_1025 | THII_1024 | Metallo-beta-lactamase family protein. | Transcriptional regulator, SpoVT_AbrB family. | 0.477 |
| THII_1025 | THII_1026 | THII_1025 | THII_1026 | Metallo-beta-lactamase family protein. | Folate-binding protein YgfZ; Belongs to the GcvT family. | 0.757 |
| THII_1026 | THII_1024 | THII_1026 | THII_1024 | Folate-binding protein YgfZ; Belongs to the GcvT family. | Transcriptional regulator, SpoVT_AbrB family. | 0.468 |
| THII_1026 | THII_1025 | THII_1026 | THII_1025 | Folate-binding protein YgfZ; Belongs to the GcvT family. | Metallo-beta-lactamase family protein. | 0.757 |
| THII_1026 | THII_2632 | THII_1026 | THII_2632 | Folate-binding protein YgfZ; Belongs to the GcvT family. | Iron-sulphur cluster biosynthesis; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.731 |
| THII_1026 | THII_3808 | THII_1026 | THII_3808 | Folate-binding protein YgfZ; Belongs to the GcvT family. | Protein involved in sulfur oxidation DsrR. | 0.612 |
| THII_1026 | THII_3867 | THII_1026 | THII_3867 | Folate-binding protein YgfZ; Belongs to the GcvT family. | Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.499 |
| THII_1026 | cysG | THII_1026 | THII_0982 | Folate-binding protein YgfZ; Belongs to the GcvT family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.483 |
| THII_1026 | erpA | THII_1026 | THII_0157 | Folate-binding protein YgfZ; Belongs to the GcvT family. | Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.795 |
| THII_1026 | gcvT | THII_1026 | THII_2082 | Folate-binding protein YgfZ; Belongs to the GcvT family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.475 |
| THII_2632 | THII_1026 | THII_2632 | THII_1026 | Iron-sulphur cluster biosynthesis; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | Folate-binding protein YgfZ; Belongs to the GcvT family. | 0.731 |
| THII_3808 | THII_1026 | THII_3808 | THII_1026 | Protein involved in sulfur oxidation DsrR. | Folate-binding protein YgfZ; Belongs to the GcvT family. | 0.612 |
| THII_3867 | THII_1026 | THII_3867 | THII_1026 | Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Folate-binding protein YgfZ; Belongs to the GcvT family. | 0.499 |
| THII_3867 | erpA | THII_3867 | THII_0157 | Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.431 |
| cysG | THII_1026 | THII_0982 | THII_1026 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Folate-binding protein YgfZ; Belongs to the GcvT family. | 0.483 |
| erpA | THII_1026 | THII_0157 | THII_1026 | Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG. | Folate-binding protein YgfZ; Belongs to the GcvT family. | 0.795 |
| erpA | THII_3867 | THII_0157 | THII_3867 | Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG. | Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. | 0.431 |
| gcvT | THII_1026 | THII_2082 | THII_1026 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Folate-binding protein YgfZ; Belongs to the GcvT family. | 0.475 |