| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0806 | THII_1493 | THII_0806 | THII_1493 | 2-polyprenyl-6-methoxyphenol 4-hydroxylase. | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.657 |
| THII_0806 | ubiA | THII_0806 | THII_3580 | 2-polyprenyl-6-methoxyphenol 4-hydroxylase. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.660 |
| THII_1493 | THII_0806 | THII_1493 | THII_0806 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 2-polyprenyl-6-methoxyphenol 4-hydroxylase. | 0.657 |
| THII_1493 | THII_1494 | THII_1493 | THII_1494 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | O-acetylhomoserine/O-acetylserine sulfhydrylase. | 0.553 |
| THII_1493 | THII_1972 | THII_1493 | THII_1972 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | Glutaredoxin-3 GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.644 |
| THII_1493 | THII_2104 | THII_1493 | THII_2104 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | BolA-like protein; Belongs to the BolA/IbaG family. | 0.993 |
| THII_1493 | THII_2632 | THII_1493 | THII_2632 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | Iron-sulphur cluster biosynthesis; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.520 |
| THII_1493 | THII_2805 | THII_1493 | THII_2805 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family. | 0.659 |
| THII_1493 | erpA | THII_1493 | THII_0157 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.524 |
| THII_1493 | gshB | THII_1493 | THII_2081 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.611 |
| THII_1493 | hscB | THII_1493 | THII_2631 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.481 |
| THII_1493 | ubiA | THII_1493 | THII_3580 | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.919 |
| THII_1494 | THII_1493 | THII_1494 | THII_1493 | O-acetylhomoserine/O-acetylserine sulfhydrylase. | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.553 |
| THII_1972 | THII_1493 | THII_1972 | THII_1493 | Glutaredoxin-3 GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.644 |
| THII_1972 | THII_2104 | THII_1972 | THII_2104 | Glutaredoxin-3 GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | BolA-like protein; Belongs to the BolA/IbaG family. | 0.682 |
| THII_2104 | THII_1493 | THII_2104 | THII_1493 | BolA-like protein; Belongs to the BolA/IbaG family. | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.993 |
| THII_2104 | THII_1972 | THII_2104 | THII_1972 | BolA-like protein; Belongs to the BolA/IbaG family. | Glutaredoxin-3 GrxC; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.682 |
| THII_2632 | THII_1493 | THII_2632 | THII_1493 | Iron-sulphur cluster biosynthesis; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.520 |
| THII_2632 | hscB | THII_2632 | THII_2631 | Iron-sulphur cluster biosynthesis; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.995 |
| THII_2805 | THII_1493 | THII_2805 | THII_1493 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family. | Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.659 |