| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0219 | THII_1923 | THII_0219 | THII_1923 | Hypothetical protein. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.661 |
| THII_0903 | THII_1923 | THII_0903 | THII_1923 | D-Ala-D-Ala carboxypeptidase. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.923 |
| THII_0903 | THII_3485 | THII_0903 | THII_3485 | D-Ala-D-Ala carboxypeptidase. | Glycosyl transferase. | 0.912 |
| THII_0903 | THII_3511 | THII_0903 | THII_3511 | D-Ala-D-Ala carboxypeptidase. | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.946 |
| THII_0903 | THII_3927 | THII_0903 | THII_3927 | D-Ala-D-Ala carboxypeptidase. | Penicillin-binding protein, 1A family. | 0.923 |
| THII_0903 | mrdA | THII_0903 | THII_3515 | D-Ala-D-Ala carboxypeptidase. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.932 |
| THII_1922 | THII_1923 | THII_1922 | THII_1923 | TPR domain-containing protein. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.814 |
| THII_1923 | THII_0219 | THII_1923 | THII_0219 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Hypothetical protein. | 0.661 |
| THII_1923 | THII_0903 | THII_1923 | THII_0903 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | D-Ala-D-Ala carboxypeptidase. | 0.923 |
| THII_1923 | THII_1922 | THII_1923 | THII_1922 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | TPR domain-containing protein. | 0.814 |
| THII_1923 | THII_2999 | THII_1923 | THII_2999 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Cell division protein. | 0.894 |
| THII_1923 | THII_3485 | THII_1923 | THII_3485 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Glycosyl transferase. | 0.926 |
| THII_1923 | THII_3511 | THII_1923 | THII_3511 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.940 |
| THII_1923 | THII_3927 | THII_1923 | THII_3927 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin-binding protein, 1A family. | 0.946 |
| THII_1923 | mltG | THII_1923 | THII_3582 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.649 |
| THII_1923 | mrdA | THII_1923 | THII_3515 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.986 |
| THII_1923 | mrdB | THII_1923 | THII_3514 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Cell cycle protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.696 |
| THII_2999 | THII_1923 | THII_2999 | THII_1923 | Cell division protein. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.894 |
| THII_2999 | mrdA | THII_2999 | THII_3515 | Cell division protein. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.612 |
| THII_2999 | mrdB | THII_2999 | THII_3514 | Cell division protein. | Cell cycle protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.563 |
