| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0596 | THII_2348 | THII_0596 | THII_2348 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Signal transduction protein. | 0.519 |
| THII_0596 | guaA | THII_0596 | THII_3737 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.552 |
| THII_0596 | ribB | THII_0596 | THII_2757 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
| THII_2136 | THII_2348 | THII_2136 | THII_2348 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Signal transduction protein. | 0.494 |
| THII_2136 | purL | THII_2136 | THII_3019 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Phosphoribosylformylglycinamidine synthase, single chain form; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.654 |
| THII_2347 | THII_2348 | THII_2347 | THII_2348 | Hypothetical protein. | Signal transduction protein. | 0.459 |
| THII_2348 | THII_0596 | THII_2348 | THII_0596 | Signal transduction protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.519 |
| THII_2348 | THII_2136 | THII_2348 | THII_2136 | Signal transduction protein. | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.494 |
| THII_2348 | THII_2347 | THII_2348 | THII_2347 | Signal transduction protein. | Hypothetical protein. | 0.459 |
| THII_2348 | THII_3529 | THII_2348 | THII_3529 | Signal transduction protein. | Acetoin utilization protein AcuB. | 0.711 |
| THII_2348 | guaA | THII_2348 | THII_3737 | Signal transduction protein. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.766 |
| THII_2348 | htpG | THII_2348 | THII_0411 | Signal transduction protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.507 |
| THII_2348 | prs | THII_2348 | THII_2308 | Signal transduction protein. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.503 |
| THII_2348 | purH | THII_2348 | THII_1633 | Signal transduction protein. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.467 |
| THII_2348 | purL | THII_2348 | THII_3019 | Signal transduction protein. | Phosphoribosylformylglycinamidine synthase, single chain form; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.699 |
| THII_2348 | ribB | THII_2348 | THII_2757 | Signal transduction protein. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.564 |
| THII_3529 | THII_2348 | THII_3529 | THII_2348 | Acetoin utilization protein AcuB. | Signal transduction protein. | 0.711 |
| THII_3529 | guaA | THII_3529 | THII_3737 | Acetoin utilization protein AcuB. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.812 |
| guaA | THII_0596 | THII_3737 | THII_0596 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.552 |
| guaA | THII_2348 | THII_3737 | THII_2348 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Signal transduction protein. | 0.766 |