| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| THII_0431 | THII_2352 | THII_0431 | THII_2352 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.902 |
| THII_2338 | THII_2352 | THII_2338 | THII_2352 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.978 |
| THII_2338 | THII_2489 | THII_2338 | THII_2489 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.489 |
| THII_2338 | THII_3187 | THII_2338 | THII_3187 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 0.928 |
| THII_2338 | nadA | THII_2338 | THII_0961 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.499 |
| THII_2338 | nadD | THII_2338 | THII_3906 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.958 |
| THII_2338 | surE | THII_2338 | THII_1715 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.902 |
| THII_2351 | THII_2352 | THII_2351 | THII_2352 | Putative aspartyl protease. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.786 |
| THII_2351 | THII_2353 | THII_2351 | THII_2353 | Putative aspartyl protease. | Transmembrane sensor domain-containing protein. | 0.741 |
| THII_2352 | THII_0431 | THII_2352 | THII_0431 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.902 |
| THII_2352 | THII_2338 | THII_2352 | THII_2338 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.978 |
| THII_2352 | THII_2351 | THII_2352 | THII_2351 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Putative aspartyl protease. | 0.786 |
| THII_2352 | THII_2353 | THII_2352 | THII_2353 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Transmembrane sensor domain-containing protein. | 0.773 |
| THII_2352 | THII_2489 | THII_2352 | THII_2489 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.998 |
| THII_2352 | THII_3187 | THII_2352 | THII_3187 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Competence/damage-inducible protein CinA domain protein; Belongs to the CinA family. | 0.922 |
| THII_2352 | nadA | THII_2352 | THII_0961 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.999 |
| THII_2352 | nadD | THII_2352 | THII_3906 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.950 |
| THII_2352 | panB | THII_2352 | THII_1562 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.666 |
| THII_2352 | surE | THII_2352 | THII_1715 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.905 |
| THII_2353 | THII_2351 | THII_2353 | THII_2351 | Transmembrane sensor domain-containing protein. | Putative aspartyl protease. | 0.741 |