THII_2360 protein (Thioploca ingrica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

THII_2360

ATP-dependent Clp protease ATP-binding protein; Belongs to the ClpA/ClpB family. (757 aa)

Predicted Functional Partners:

clpS

0.977

hscA

0.857

dnaK

0.857

clpP

0.851

grpE

0.738

THII_1545

0.723

htpG

0.717

THII_0876

0.701

THII_0349

0.670

THII_2285

0.670

Your Current Organism:

Thioploca ingrica

NCBI taxonomy Id: 40754
Other names: T. ingrica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
THII_0349	THII_2285	THII_0349	THII_2285	Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	0.902
THII_0349	THII_2360	THII_0349	THII_2360	Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.	ATP-dependent Clp protease ATP-binding protein; Belongs to the ClpA/ClpB family.	0.670
THII_0349	dnaK	THII_0349	THII_2710	Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.464
THII_0349	grpE	THII_0349	THII_2711	Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.	GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.462
THII_0349	hscA	THII_0349	THII_2630	Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.464
THII_0349	htpG	THII_0349	THII_0411	Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.	0.489
THII_0876	THII_1545	THII_0876	THII_1545	Protease subunit of ATP-dependent protease.	Secreted protein.	0.569
THII_0876	THII_2360	THII_0876	THII_2360	Protease subunit of ATP-dependent protease.	ATP-dependent Clp protease ATP-binding protein; Belongs to the ClpA/ClpB family.	0.701
THII_0876	clpP	THII_0876	THII_0147	Protease subunit of ATP-dependent protease.	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.540
THII_0876	grpE	THII_0876	THII_2711	Protease subunit of ATP-dependent protease.	GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.468
THII_1545	THII_0876	THII_1545	THII_0876	Secreted protein.	Protease subunit of ATP-dependent protease.	0.569
THII_1545	THII_2360	THII_1545	THII_2360	Secreted protein.	ATP-dependent Clp protease ATP-binding protein; Belongs to the ClpA/ClpB family.	0.723
THII_1545	clpP	THII_1545	THII_0147	Secreted protein.	ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.652
THII_2285	THII_0349	THII_2285	THII_0349	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.	0.902
THII_2285	THII_2360	THII_2285	THII_2360	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	ATP-dependent Clp protease ATP-binding protein; Belongs to the ClpA/ClpB family.	0.670
THII_2285	dnaK	THII_2285	THII_2710	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.464
THII_2285	grpE	THII_2285	THII_2711	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.462
THII_2285	hscA	THII_2285	THII_2630	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.464
THII_2285	htpG	THII_2285	THII_0411	Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.	0.489
THII_2360	THII_0349	THII_2360	THII_0349	ATP-dependent Clp protease ATP-binding protein; Belongs to the ClpA/ClpB family.	Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.	0.670