close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THII_2581Sigma-54 dependent DNA-binding response regulator. (452 aa)    
Predicted Functional Partners:
THII_2580
Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
 
 0.935
THII_2579
Proline rich signal peptide protein.
 
     0.789
THII_1254
DNA-directed RNA polymerase specialized sigma subunit, sigma54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.732
THII_2578
Ribosomal RNA small subunit methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
       0.657
THII_0803
Histidine kinase.
 
 
 
 0.545
THII_0636
Signal transduction histidine kinase.
  
 
 0.530
THII_1121
Sensory transduction protein kinase.
 
 0.515
THII_1283
Chemotaxis protein histidine kinase-like protein.
  
 
0.479
THII_1988
Chemotaxis protein histidine kinase-like protein.
  
 
0.479
THII_2963
PAS domain S-box/diguanylate cyclase (GGDEF) domain-containing protein.
  
 
 0.468
Your Current Organism:
Thioploca ingrica
NCBI taxonomy Id: 40754
Other names: T. ingrica
Server load: low (32%) [HD]